Immunoelectron microscopy is a highly precise and sensitive technique that combines the specificity of antigen-antibody reactions with the high resolution of electron microscopy to perform localization analysis of antigens at the subcellular and ultrastructural levels.
Application Areas:Immunoelectron microscopy combines the high specificity and sensitivity of antigen-antibody reactions in immunology with the visibility of morphology in histochemistry. This technique allows the study of immune responses at the tissue, cellular, subcellular, and molecular levels. In the field of transmission electron microscopy, it has been successfully applied to the labeling of antigens and macromolecules in viruses, bacteria, red blood cells, bone marrow cells, lymphocytes, platelets, kidney cells, liver cells, neurons, pituitary tissue, the duodenum, and more.